WELCOME TO THE ZOMORRODI LAB!
The Zomorrodi Lab constructs computational mechanistic models of the microbiome and host to better understand the pathogenesis of human diseases and to streamline the design of personalized treatments.
We are part of the Mucosal Immunology and Biology Research Center (MIBRC) at MassGeneral Hospital for Children and Harvard Medical School
>> Open positions: We are currently recruiting postdoctoral and PhD candidates for an NIH-funded project in the field of the human microbiome. We are also recruiting students interested in conducting thesis or volunteer research on the applications of Large Language Models (LLMs) in healthcare and AI for multi-omics analysis. Please visit this page for more information.
RECENT PUBLICATIONS
- Alessi D, McCreery CV and Zomorrodi AR, Unraveling the Link between Nutrition and Metabolic Syndrome Risk through In Silico Dietary Interventions, bioRxiv, 2024, DOI: 10.1101/2024.04.29.591234
- McCreery CV, Alessi D, Mollo K, Fasano A, and Zomorrodi AR, Investigating intestinal epithelium metabolic dysfunction in Celiac Disease using personalized genome-scale models, bioRxiv, 2024, DOI: 10.1101/2024.04.29.591234.
- Eshoa E and Zomorrodi AR, Precision game engineering through reshaping strategic payoffs. arXiv, 2024, DOI: arXiv:2404.00153
- Tran T, Senger S, Baldassarre M, Brosnan RA, Cristofori F, Crocco M, De Santis S, Elli L, Faherty CS, Francavilla R, Goodchild-Michelman I, Kenyon VA, Leonard MM, Lima RS, Malerba F, Montuori M, Morelli A, Norsa L, Passaro T, Piemontese P, Reed JC, Sansotta N, Valitutti F, Zomorrodi AR, Fasano A, Team CDGEMM. Novel Bacteroides vulgatus strain protects against gluten-induced break of human celiac gut epithelial homeostasis: a pre-clinical proof-of-concept study. Pediatr Res. 2024. Epub 20240104. doi: 10.1038/s41390-023-02960-0. PubMed PMID: 38177249.
- Zomorrodi AR, Hemez C, Arranz-Gibert P, Wu T, Isaacs FJ, Segrè D. Computational design and engineering of an Escherichia coli strain producing the nonstandard amino acid para-aminophenylalanine. iScience. 2022;25(7):104562, PMID: 35789833.
NEWS
- September 2024 – Elie Eshoa’s paper was accepted in Scientific Reports. Wonderful job and congratulations!
- September 2024 – Ali was a featured speaker at the FrontLine Genomics webinar series, “Transforming Human Health through Microbiome”. He shared Insights on the potential of long-read sequencing technologies to advance human microbiome research.
- September 2024 – Xinyi “Riddle” Chen a Biostatistics master’s student at Boston University joins the lab. Welcome!
- August 2024 – We are excited to welcome Nicky Medearis and Mengdi “Kim” Chai to our lab! Nicky, a master’s student in Computer Science at MIT, and Kim, a master’s student at HSPH, will be joining our team to work on their master’s theses.
- July 2024 – Ali delivers a lecture on microbiome multi-omics analysis at the MGH Digestive Disease Summer Research Program.
- June 2024 – BIG NEWS!! The NIH supports the lab’s research on the role of the gut microbiome in Celiac Disease through a 1.75M R01 award!
- June 2024 – Harvard master’s student Rex Manglicmot joins the lab. Welcome!
- June 2024 – Ali presents at the Festival of Genomics & Bio Data Boston 2024 on the role of probiotics in the development of the gut microbiome in pre-term infants.
- April 2024 – Izzy and Drew present their research in the 2024 MGfC Research Day.
- March 2024 – Harvard master’s students Ellie Zhang, Jacob Yu, Jiayi Sun and Kevin Wu, and undergraduate student Jack Tian join the lab. Welcome!
- February 2024 – Ali wins an MGH Executive Committee on Research (ECOR) Interim Support Funding.
ZOMORRODI LAB ON TWITTER
