WELCOME TO THE ZOMORRODI LAB!
The Zomorrodi Lab constructs computational mechanistic models of the microbiome and host to better understand the pathogenesis of human diseases and to streamline the design of personalized treatments.
We are part of the Mucosal Immunology and Biology Research Center (MIBRC) at MassGeneral Hospital for Children and Harvard Medical School
>> Open positions: We are currently recruiting PhD candidates for an NIH-funded project in the field of the human microbiome. We are also recruiting students interested in conducting thesis or volunteer research on the applications of Large Language Models (LLMs) in healthcare and AI for multi-omics analysis. Please visit this page for more information.
RECENT PUBLICATIONS
- McCreery CV, Alessi D, Mollo K, Fasano A, Zomorrodi AR. Investigating intestinal epithelium metabolic dysfunction in celiac disease using personalized genome-scale models. BMC Med. 2025;23(1):95. Epub 20250221. doi: 10.1186/s12916-025-03854-0. PubMed PMID: 39984962.
- Eshoa E, Zomorrodi AR. Precision game engineering through reshaping strategic payoffs. Sci Rep. 2024;14(1):25226. Epub 20241024. doi: 10.1038/s41598-024-72543-4. PubMed PMID: 39448647.
- Alessi D, McCreery CV and Zomorrodi AR, Unraveling the Link between Nutrition and Metabolic Syndrome Risk through In Silico Dietary Interventions, bioRxiv, 2024, DOI: 10.1101/2024.04.29.591234
- Tran T, Senger S, Baldassarre M, Brosnan RA, Cristofori F, Crocco M, De Santis S, Elli L, Faherty CS, Francavilla R, Goodchild-Michelman I, Kenyon VA, Leonard MM, Lima RS, Malerba F, Montuori M, Morelli A, Norsa L, Passaro T, Piemontese P, Reed JC, Sansotta N, Valitutti F, Zomorrodi AR, Fasano A, Team CDGEMM. Novel Bacteroides vulgatus strain protects against gluten-induced break of human celiac gut epithelial homeostasis: a pre-clinical proof-of-concept study. Pediatr Res. 2024. Epub 20240104. doi: 10.1038/s41390-023-02960-0. PubMed PMID: 38177249.
- Zomorrodi AR, Hemez C, Arranz-Gibert P, Wu T, Isaacs FJ, Segrè D. Computational design and engineering of an Escherichia coli strain producing the nonstandard amino acid para-aminophenylalanine. iScience. 2022;25(7):104562, PMID: 35789833.
NEWS
- January 2025 – Chloe’s paper was accepted in BMC Medicine! Congratulations and great job, Chloe!
- January 2025 – Ali was promoted to Assistant Professor Pediatrics at Harvard Medical School and MGH!
- January 2025 – Yixuan Huang a master’s student and Ryan Noorbakhsh and Jasmine Andresol undergraduate students at Harvard join the lab. Welcome!
- December 2024 – Ellie Zhang, Jiayi Sun, and Jacob Yu graduated from Harvard and move on to industry positions. Congratulations!
- October 2024 – Aarush Garg and undergraduate student at Northeastern University and Ameer Haidar a senior undergraduate student at MCPHS joins the lab. Welcome!
- September 2024 – Elie Eshoa’s paper was accepted in Scientific Reports. Wonderful job and congratulations!
- September 2024 – Ali was a featured speaker at the FrontLine Genomics webinar series, “Transforming Human Health through Microbiome”. He shared Insights on the potential of long-read sequencing technologies to advance human microbiome research.
- September 2024 – Xinyi “Riddle” Chen a Biostatistics master’s student at Boston University joins the lab. Welcome!
- August 2024 – We are excited to welcome Nicky Medearis and Mengdi “Kim” Chai to our lab! Nicky, a master’s student in Computer Science at MIT, and Kim, a master’s student at HSPH, will be joining our team to work on their master’s theses.
- July 2024 – Ali delivers a lecture on microbiome multi-omics analysis at the MGH Digestive Disease Summer Research Program.
- June 2024 – BIG NEWS!! The NIH supports the lab’s research on the role of the gut microbiome in Celiac Disease through a 1.75M R01 award!
ZOMORRODI LAB ON TWITTER
